亚洲传统医药

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Overview of chemical constituents and pharmacological activities of Piper longum Linn.

Liwei Lu, Le Zhou, Yuxi Wang, Zhuoyang Cheng, Jie Wang, Xiaoxiao Huang*, Shaojiang Song*   

  1. Department of Natural Products Chemistry, Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China
  • 收稿日期:2018-09-19 修回日期:2018-11-30 出版日期:2019-06-20 发布日期:2018-11-30

Overview of chemical constituents and pharmacological activities of Piper longum Linn.

Liwei Lu, Le Zhou, Yuxi Wang, Zhuoyang Cheng, Jie Wang, Xiaoxiao Huang*, Shaojiang Song*   

  1. Department of Natural Products Chemistry, Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China
  • Received:2018-09-19 Revised:2018-11-30 Online:2019-06-20 Published:2018-11-30
  • Contact: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Rd., Shenyang 110016, China; Tel.: +86-24-23986510 (Xiaoxiao Huang); E-mail: xiaoxiao270@163.com (Xiaoxiao Huang); School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Rd., Shenyang 110016, China; Tel.: +86-24-23986510 (Shaojiang Song); E-mail: songsj99@163.com (Shaojiang Song)

摘要: Piper longum Linn. is a native of the Indo-Malaya region, belongs to the family Piperaceae. It is a slender aromatic climber widely distributed in the tropical and subtropical regions. As a traditional ethnic drug, P. longum contains various chemical constituents such as alkaloids, volatile oil and lignans. The extract of P. longum has been reported to show various activities like antitumor, antioxidant and hepatoprotective activity. Hence, this paper is presented as a review centered on the main chemical constituents and pharmacological effects of P. longum, aiming at its further development and potential value.

关键词: Piper longum Linn., chemical constituents, pharmacological effects, research review

Abstract: Piper longum Linn. is a native of the Indo-Malaya region, belongs to the family Piperaceae. It is a slender aromatic climber widely distributed in the tropical and subtropical regions. As a traditional ethnic drug, P. longum contains various chemical constituents such as alkaloids, volatile oil and lignans. The extract of P. longum has been reported to show various activities like antitumor, antioxidant and hepatoprotective activity. Hence, this paper is presented as a review centered on the main chemical constituents and pharmacological effects of P. longum, aiming at its further development and potential value.

Key words: Piper longum Linn., chemical constituents, pharmacological effects, research review