亚洲传统医药

• Review • 上一篇    

Research review in the main chemical constituents and pharmacological effects of Daphne acutiloba Rehd.

Tianming Lv, Rui Guo, Xiaoxiao Huang*   

  1. Department of Natural Products Chemistry, Key Laboratory of Computational ChemistryBased Natural Antitumor drug Research & Development, Ministry of Education, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China
  • 收稿日期:2018-11-19 修回日期:2019-01-28 出版日期:2019-06-20 发布日期:2019-01-28

Research review in the main chemical constituents and pharmacological effects of Daphne acutiloba Rehd.

Tianming Lv, Rui Guo, Xiaoxiao Huang*   

  1. Department of Natural Products Chemistry, Key Laboratory of Computational ChemistryBased Natural Antitumor drug Research & Development, Ministry of Education, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China
  • Received:2018-11-19 Revised:2019-01-28 Online:2019-06-20 Published:2019-01-28
  • Contact: School of Traditional Chinese Materia, Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, Shenyang Pharmaceutical University, Shenyang 110016, People’s Republic of China; Tel.: +86-24-23986486; Fax: +86-24-23986486.

摘要: Daphne acutiloba Rehd., belonging to Daphne genus of Thymelaeaceae is an evergreen shrub mainly distributed in the west of China. The roots, stem barks, leaves and fruits of this plant had been used as folk medicines for the treatment of rheumatoid arthriths, apoplesia and stomachache ache. Daphne diterpenes and tieranes diterpenes, guaiacane type sesquiterpene, lignans, diflavane and flavonoids, sterides, aliphatics and phenols were isolated from Daphne acutiloba Rehd. Researches demonstrated that the main chemical constituents of D. acutiloba Rehd. have multiple activities and good development prospect. This paper is presented as a review centering on the main chemical constituents and pharmacological effects of D. acutiloba Rehd. for the further research and development of this plant.

关键词: Daphne acutiloba Rehd., chemical constituents, pharmacological effects, research review

Abstract: Daphne acutiloba Rehd., belonging to Daphne genus of Thymelaeaceae is an evergreen shrub mainly distributed in the west of China. The roots, stem barks, leaves and fruits of this plant had been used as folk medicines for the treatment of rheumatoid arthriths, apoplesia and stomachache ache. Daphne diterpenes and tieranes diterpenes, guaiacane type sesquiterpene, lignans, diflavane and flavonoids, sterides, aliphatics and phenols were isolated from Daphne acutiloba Rehd. Researches demonstrated that the main chemical constituents of D. acutiloba Rehd. have multiple activities and good development prospect. This paper is presented as a review centering on the main chemical constituents and pharmacological effects of D. acutiloba Rehd. for the further research and development of this plant.

Key words: Daphne acutiloba Rehd., chemical constituents, pharmacological effects, research review