Preparation, physicochemical properties and antioxidant activity of genistein phospholipid complexes

Abstract

Abstract: Genistein phospholipid complex (GS-PC) was produced in order to increase the solubility and antioxidant activity of genistein (GS), an insoluble natural polyphenol compound. By using the solvent evaporation process, GS-PC was produced. Several characteristics techniques were used to confirm the production of GS-PC, and its physicochemical characteristics and antioxidant activity were investigated. The outcome showed that GS-PC had a recombination rate of 96.84% ± 0.51%. The characterization results confirmed that GS-PC was formed by the intermolecular interaction between GS and phospholipids. In vitro antioxidant studies showed that GS-PC had a certain scavenging ability on DPPH free radicals, ABTS free radicals and hydroxyl free radicals. In summary, the results of this study indicated that GS-PC could be used as a formula to improve its solubility and antioxidant activity.

Key words: genistein, phospholipid complex, physical and chemical properties, antioxidant

Ming Yang, Dan Zhang, Honghui Zhao, Shuping Wang, Xu Zhao. Preparation, physicochemical properties and antioxidant activity of genistein phospholipid complexes[J]. Journal of Polyphenols, 2024, 6(4): 141-149.

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